Use of Oral Paracetamol as Premedication to Reduce Propofol Induced Pain During Induction of General Anesthesia
Introduction:Propofol is the most frequently used intravenous anesthestic agent for induction of anesthesia inspite of pain on injection. Various pharmacological and non-pharmacological methods have been used to alleviate propofol induced pain. Paracetamol(PCM) is the most common analgesic available, which is cheap, easily available and with minimal side-effects. There are various international studies which showed that paracetamol reduced the propofol induced pain.
Methods:It is a descriptive, cross-sectional study conducted at operation theater of Kist Medical College. The sample size of 80 individuals was calculated using Cochrane Formula. This study was conducted from July 2021 to December 2021 A.D. Patients from 18-60 years of age and within ASA I-II undergoing elective surgery, who had no contraindication to paracetamol were included in the study.
Results:Out of 40 patients who received PCM 57.5% had mild pain, 20 % had moderate pain, 2.5% had severe pain whereas 20 % of them had no pain. Among those who did not receive PCM, 2.5% had mild pain, 52.5% had moderate pain and 45% had severe pain. The average pain score on NRS score was 2.32 among PCM received group and 6.32 among those who did not receive PCM.
Conclusion:It was found that premedication with paracetamol is helpful to alleviate pain induced by propofol injection during induction of general anesthesia.
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